11/20/2008
Thursday morning

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The U.S. pharmaceutical industry began 1994 with a good deal of trepidation, aware that it was likely to absorb much public criticism for prices and profiteering when Congress began considerations on a new health care bill. Drug manufacturers had been singled out as villains for being major contributors to the problem of health care costs, but...
The transdermal application of drugs provides an alternate method for applying drugs to achieve a systemic, rather than local, effect. The administration of a drug through the skin not only minimizes the metabolism of the drug before it reaches the rest of the body but also eliminates the high and low blood levels associated with oral...
Study of the factors that influence the movement of drugs throughout the body is called pharmacokinetics, which includes the absorption, distribution, localization in tissues, biotransformation, and excretion of drugs. The study of the actions of the drugs and their effects is called pharmacodynamics. Before a drug can be effective, it must be...
any chemical substance that affects the functioning of living things and the organisms (such as bacteria, fungi, and protozoans) that infect them. Pharmacology, the science of drugs, deals with all aspects of drugs in medicine, including their mechanism of action, physical and chemical properties, metabolism, and therapeutics and prophylaxis.
Even before 1993 drew to a close, it brought down a deluge of bad news on the heads of U.S. pharmaceutical industry executives. The image of the big companies as blue-chip, inevitably profitable cash cows for investors was smashed. The first blow was delivered by Pres. Bill Clinton's national health plan, which presented a real threat to...
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