1/7/2009
Wednesday morning

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Even before 1993 drew to a close, it brought down a deluge of bad news on the heads of U.S. pharmaceutical industry executives. The image of the big companies as blue-chip, inevitably profitable cash cows for investors was smashed. The first blow was delivered by Pres. Bill Clinton's national health plan, which presented a real threat to...
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The purpose of using drugs is to relieve symptoms, treat infection, reduce the risk of future disease, and destroy selected cells such as in the chemotherapeutic treatment of cancer. The best treatment, however, may not require a drug at all. Recognizing that no effective medication exists is just as important as knowing which one to select.
The transdermal application of drugs provides an alternate method for applying drugs to achieve a systemic, rather than local, effect. The administration of a drug through the skin not only minimizes the metabolism of the drug before it reaches the rest of the body but also eliminates the high and low blood levels associated with oral...
With very few exceptions, in order for a drug to affect the function of a cell, an interaction at the molecular level must occur between the drug and some target component of the cell. In most cases the interaction consists of a loose, reversible binding of the drug molecule, although some drugs can form strong chemical bonds with their target...
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